Detroit (10-18-4, 24 points) travels to Nashville (14-17-1, 29 points) for a Tuesday/Thursday series at Bridgestone Arena as both clubs hope to gain ground in the Central Division.
The Predators come into the series having won three of their last four games overall, including a 4-3 shootout win against the Dallas Stars on Sunday.
The Red Wings also played the Stars last, beating Dallas on March 18 to earn five of eight points against three of the best teams in the NHL, but Detroit suffered a setback Saturday night, with a 3-0 loss to the defending Stanley Cup runners-up.
Wings coach Jeff Blashill said he was pleased with his team's process and progress throughout their six-game homestand, in which Detroit went 3-2-1.
"As it went along, we played better and better defensively. I thought as it went along, we played faster and we managed the puck better. Those three things are real important," Blashill said. "We've got to manage the puck. When you manage it and you execute, you play faster out of your end and faster in the neutral zone, and you have to defend well to have a chance to win."