| Opponent | Date | Time (ET) | Location | |
|---|---|---|---|---|
| Boston Bruins | 9/19/17 | 7:00 p.m. | TD Garden | |
| Pittsburgh Penguins | 9/20/17 | 7:00 p.m. | PPG Paints Arena | |
| Chicago Blackhawks | 9/21/17 | 8:30 p.m. | United Center | |
| Boston Bruins | 9/23/17 | 7:00 p.m. | Little Caesars Arena | |
| Pittsburgh Penguins | 9/25/17 | 7:30 p.m. | Little Caesars Arena | |
| Chicago Blackhawks | 9/28/17 | 7:30 p.m. | Little Caesars Arena | |
| Toronto Maple Leafs | 9/29/17 | 7:30 p.m. | Little Caesars Arena | |
| Toronto Maple Leafs | 9/30/17 | 7:00 p.m. | TBD |