Thornton is the leading active scorer in the NHL, the heartbeat of the locker room, a matchup problem as a third-line center and a mainstay on the power play.
Without him, Joe Pavelski will move from right wing on the first line to center. With forward Micheal Haley also day to day with a leg injury, forwards Joonas Donskoi and Lukas Radil will dress for the first time in the series.
Donskoi hasn't scored in his past 34 games; however, his last goal was the winner in a 3-2 victory against the Golden Knights at T-Mobile Arena on Jan. 10.
"Sometimes you feel like you're hot in certain buildings, and I think that's the mental thought you have before the game," Donskoi said. "I've been sitting out now for a while, and I'm full of energy. I just want to get out there and help the team."