Bouwmeester experienced a cardiac episode Tuesday in their previous game, against the Anaheim Ducks, which was postponed.
The Blues, 2-5-2 in their past nine games, lead the second-place Colorado Avalanche by one point; the Avalanche host the Washington Capitals on Thursday.
Goalie Jordan Binnington will start for St. Louis, which is 1-6-1 in its past eight road games.
Goalie Malcolm Subban will make his first start since Jan. 31 for the Golden Knights, who have lost two straight. Vegas is tied with the Calgary Flames and Arizona Coyotes for third place in the Pacific Division.