The Sharks, 6-1-0 in their past seven games and 15-4-1 in their past 20, also can clinch with if they get one point and the Minnesota Wild lose to the New York Rangers in any fashion; or if Minnesota loses in regulation and the Chicago Blackhawks lose to the Montreal Canadiens in any fashion.
San Jose trails the Calgary Flames by one point for first place in the Pacific Division and Western Conference.
Forward Evander Kane will return to the Sharks lineup after missing seven games with a mid-body injury. During that stretch, Kane was away from the team for five days to be with his wife after a miscarriage.
The Predators, 3-4-0 in their past seven games, is in second place in the Central Division, one point behind the Winnipeg Jets, who host the Flames earlier Saturday.