Fleury, who is seventh in wins and second behind New York Rangers goalie Henrik Lundqvist (453) among active NHL goalies, is coming off his second shutout of the season, a 6-0 victory against the Calgary Flames on Sunday.
The Golden Knights are looking to win consecutive games for the first time since Oct. 17-19. They have gone 4-6-3 since then.
The Maple Leafs, playing the second of a six-game road trip, are 0-4-1 in their past five games after winning their previous three. Goalie Frederik Andersen is expected to start.