Washington, which is beginning a three-game Canada road trip, is coming off a 6-5 shootout loss to the Florida Panthers on Friday and has allowed 18 goals in its past four games (1-2-1).
Goalie Braden Holtby, who was pulled after allowing four goals on 11 shots against the Panthers, will start for the Capitals.
Vancouver is 4-1-0 in its past five games, including a 2-1 overtime win against the Boston Bruins on Saturday, and will start goalie Anders Nilsson, who is 3-1-0 with a 2.26 goals-against average and .925 save percentage.