Binnington, who stopped 30 of 31 shots in a 6-1 win against the New York Islanders in his last start on Saturday, will be looking to help the Blues extend their season-long winning streak to seven games in Buffalo.
The Blues have collected points in nine straight games (8-0-1) dating back to March 28 and have scored at least four goals in each of those games as they battle to secure their spot - and positioning - in the Stanley Cup Playoffs.
Below is a projected lineup based on Thursday's morning skate.