Craig Anderson allowed four goals on 26 shots and was replaced by Mike Condon at 9:53 of the second period. Condon made 13 saves on 17 shots.
It was the first time the Blackhawks had four power-play goals in a game this season; their previous high was two, five times. Kane scored on the power play and had an assist on the other three goals with the man-advantage.
"I've never done it before in the NHL. It's a good feeling," Kane said of his five-point game. "I think one of the things we really haven't really had the fortune of this year is to have a hot power play. You saw that tonight. We were kind of making easy plays. I don't think it was anything special throughout the game. Just making the right play out there and finishing off some plays. It was a good night for everyone."
Said Schmaltz of playing with Kane: "He's just so effortless and so fun to watch and be a part of, being on his line. It's a treat every night. He makes something spectacular happen every night, it seems like. To be able to watch him and play with him is pretty amazing. I think he could have multiple points every night."
After Panik made it 1-0 at 18:51 of the first period, the Blackhawks got three goals in 4:39 in the second. Sharp made it 2-0 at 5:14, Schmaltz scored on the power play at 8:15 for a 3-0 lead, and Toews scored off the rebound of a Jordan Oesterle shot at 9:53.
Anderson was pulled after Toews scored to make it 4-0.
"When the snowball starts rolling, it's hard to make it stop," Senators captain Erik Karlsson said. "They were obviously feeling the game, and we were not."
Stone (10:35) and Brassard (16:39) scored to get the Senators within 4-2, but Schmaltz (17:33) and Rutta (19:07) each scored a power-play goal to make it 6-2.
Forsberg had an assist on Rutta's goal for his first NHL point.
In the third period, Toews scored his second of the night at 3:24 to make it 7-2, and Kane scored to make it 8-2 at 10:01 with Senators defenseman Dion Phaneuf in the penalty box for slashing Lance Bouma.
