Washington (51-17-8) has won six games in a row and leads the NHL with 110 points with six games left on its schedule.
The Capitals appear poised to win the Presidents' Trophy for earning the most points of any team in the League.
Washington has earned at least one point in six of its past eight games against the Coyotes (5-2-1).
Goalie Braden Holtby is expected to start after sitting out the team's 5-3 win over Colorado on Wednesday. Holtby has posted at least 40 wins in three consecutive seasons. Only Martin Brodeur (2005-08) and Evgeni Nabokov (2007-10) also have accomplished that feat. Holtby ranks second in the NHL with a 2.04 goals-against average and is third with a .926 save percentage.
Captain Alex Ovechkin, who leads the team and ranks 11th in the NHL with 33 goals, has produced 15 points (six goals, nine assists) in 13 career games against the Coyotes.
Center Nicklas Backstrom has notched 11 points (one goal, 10 assists) in his past six games to bring his point total to a team-leading 82.
Washington has scored 34 power-play goals in its past 37 games and has not allowed a power-play goal in five consecutive games.
"I wouldn't say our game has been totally complete," Head Coach Barry Trotz said after the morning skate on Friday. "For the most part this group has stayed focused on being consistent and it has a willingness to keep learning rather than ignoring things that come up in our game. We're open-minded about getting things fixed. We're trying to finish first in the Metro and get any advantage possible, but and team you get in the (Stanley Cup Playoffs) is going to be tough."