Seider had a goal and four assists to tie the team record for points in a game by a defenseman for the Red Wings (41-29-9), who had lost five of six (1-4-1).
Patrick Kane had a goal and two assists to move within one point of 1,400 for his career, and Alex DeBrincat became the first Red Wings player with 40 goals since Marian Hossa in 2008-09.
John Gibson made 13 saves on 15 shots before leaving the game with an undisclosed injury. Cam Talbot finished the game, allowing one goal on 11 shots.
Detroit remained three points behind the Ottawa Senators for the second wild card into the Stanley Cup Playoffs from the Eastern Conference. Ottawa won 5-1 against the Florida Panthers on Thursday.
Porter Martone had a goal and an assist for the Flyers (40-27-12), whose three-game winning streak ended. Dan Vladar was removed after allowing four goals on eight shots. Samuel Ersson allowed two goals on 15 shots.
The Flyers’ lead for third place in the Metropolitan Division went down to one point ahead of the New York Islanders, who won 5-3 against the Toronto Maple Leafs on Thursday. The Islanders are also tied with Detroit, three points behind Ottawa in the wild card.
DeBrincat gave the Red Wings a 1-0 lead with a power-play goal at 2:28 of the first period. Lucas Raymond got him the puck in the low slot and he surprised Vladar with a quick backhand over his blocker.
Philadelphia made it 1-1 at 13:24 when Christian Dvorak deflected Martone’s low shot past Gibson for his 18th goal.
The Flyers took a penalty at the 20-minute mark of the first period and another at 15 seconds of the second. Detroit quickly took advantage, scoring a pair of power-play goals.
Seider put them ahead 2-1 at 32 seconds, beating Vladar with a high slap shot after a pass from Kane. Kane also set up Larkin for Detroit’s third power-play goal of the game, a wrist shot from the low slot at 1:50.
The Red Wings took two penalties, giving the Flyers 28 seconds of 5-on-3, but they killed the first before Albert Johansson’s blocked shot set Larkin away on a breakaway. He scored the short-handed goal to make it 4-1 at 4:56, giving him three points in the period.
Martone’s power-play goal made it 4-2 at 9:25, and Gibson left the game shortly afterward. He was involved in a heavy collision with Owen Tippett in the first minute of the period.
Kane made it 5-2 at 7:01 of the third period, tapping in Simon Edvinsson’s pass at the back door, and Larkin finished off Detroit’s first hat trick of the season and his third in the NHL at 11:39.
Former Red Wing Luke Glendening made it 6-3 at 18:09.
