"In close games, you can't make mistakes that are going to cost your team an opportunity to stay in it, and that's what happened there at the end," said Smith, who made 32 saves. "Honest mistake there. I thought the puck was moving faster than it was, got out of my net, and by the time I realized it wasn't getting to me, I was in trouble.
"Obviously, it's disappointing. We go back and get a goal there on the power play, and that (Nylander) goal turns into a pretty big mistake. Obviously, that's disappointing. You're disappointed in yourself when that happens. You let the team down, but you move on. We had a good road trip, so we'll go home and regroup here."
Oilers center Connor McDavid's five-game point streak ended (12 points; four goals, eight assists).
Kane gave the Blackhawks a 1-0 lead at 4:11 of the second period, scoring with a quick shot from the left circle off a Dylan Strome face-off win.