ST. LOUIS -- Auston Matthews and Zach Hyman each scored two goals for the Toronto Maple Leafs in a 5-2 win against the St. Louis Blues at Enterprise Center on Saturday.
Toronto (14-13-4) chased Blues goalie Jordan Binnington for the first time in a regular-season game after he allowed four goals on 11 shots in the first period. Binnington has lost two straight games in the regular season for the first time in his NHL career.
"We got off to a good start," Matthews said. "[Frederik] Andersen made some big saves, and we got to roll all four lines."
[WATCH: All Maple Leafs vs. Blues highlights]
Jason Spezza scored, Mitchell Marner had two assists, and Andersen made 26 saves for the Maple Leafs, who had not won in their previous seven games against the Blues (0-4-3).
Ivan Barbashev and David Perron scored for the Blues (18-7-6), who lost their second straight. Jake Allen allowed one goal on 16 shots in relief of Binnington.
Video: TOR@STL: Matthews slips wrist shot under Binnington
"We gave them some pretty good chances, obviously the shorthanded one," Blues defenseman Alex Pietrangelo said. "We were a little bit sloppy with the puck, we knew we had to defend against these guys, obviously highly skilled. Just weren't ready. It happens. At the start of the first period, I thought we had some decent looks. Once that team gets momentum offensively, they're going to keep going. We know what we did wrong."
The Maple Leafs led 4-1 after the first period, scoring three times in a span of four shots.
Hyman made it 1-0 at 2:50 on a one-timer from the left face-off circle that Binnington got a piece of after a Zach Sanford turnover in the neutral zone.
Video: TOR@STL: Hyman nets one-timer from the circle
Barbashev tied it 1-1 at 4:25 from the slot before Matthews made it 2-1 at 6:51. Jay Bouwmeester missed the puck at the Toronto blue line, and Matthews used St. Louis defenseman Justin Faulk as a screen to beat Binnington.
Hyman scored shorthanded on a 2-on-0 breakaway to make it 3-1 at 9:12 after Pierre Engvall picked off an errant Perron pass.
"You give up a shorthanded goal, there's just no reason for that to happen," Blues coach Craig Berube said. "... We made a couple mistakes, mistakes that you shouldn't make."
Spezza scored a power-play goal at 12:57 from near the blue line to extend the lead to 4-1 and chase Binnington.
"We played with confidence a little bit better," Spezza said. "We had some pretty good moments and got rewarded with some of our chances."
Video: TOR@STL: Spezza nets PPG through screen in front
Matthews scored on the power play at 9:29 of the second period to make it 5-1. The puck caromed to the side of the net, and he was able to lift a shot over Allen.
Matthews scored for the first time in six games and leads Toronto with 18 goals. He had one goal in seven previous games against St. Louis.
"It's a huge relief," Matthews said. "It kind of gets you going, gets your confidence back. I've just got to try and get my chances, shoot the puck as much as I can, and eventually I think it's going to go in."
Perron redirected Pietrangelo's shot from the right point to get the Blues within 5-2 at 2:02 of the third period.
Video: TOR@STL: Hyman pots SHG on 2-on-0 for second goal
They said it
"It's got to feel good for him. I had full confidence it was going to fall in for him." -- Maple Leafs coach Sheldon Keefe on Auston Matthews scoring for the first time in six games
"We're not worried about him. He's always responded well and the whole season he's been our best player. I thought tonight there were kind of a couple missed shots and bad bounces that happened that do happen in the game of hockey and it's not his fault. I'm not worried about him at all. He's going to do his thing. We just have to be better in front of him to make it easier for him." -- Blues center Ryan O'Reilly on goalie Jordan Binnington
Need to know
Hyman has three goals in the past two games. … The Maple Leafs are 5-3-0 since Keefe took over for Mike Babcock on Nov. 20. ... Toronto had not won against St. Louis since Jan. 2, 2016. ... Perron has 10 points (four goals, six assists) in his past 10 games. ... Sanford sustained an upper-body injury in the first period.
Maple Leafs: At the Vancouver Canucks on Tuesday (10 p.m. ET; SNP, SNO, NHL.TV)
Blues: At the Buffalo Sabres on Tuesday (7:30 p.m. ET; NBCSN, FS-MW, NHL.TV)
Video: Matthews, Hyman lead Maple Leafs past Blues, 5-2