Frost, who was recalled from Lehigh Valley of the American Hockey League on Monday, made it 4-2 at 14:20 of the second when he made a quick move to get in front of the net and flipped in a high backhand.
"I was kind of low in the D zone, and [Konecny] made a really nice pass," Frost said. "I saw a bit of room, and at first I was looking pass, and then I saw I had a lane to the net. I think the goalie put his stick out, so I just tried to go short side with him, and luckily it went in. I was a little shocked at first, but, yeah, great feeling."
Hoffman scored an empty-net goal at 17:28 of the third for the 5-2 final.
Philadelphia outshot Florida 14-5 in the third period.
"It was a good home win," Panthers coach Joel Quenneville said. "We had some stretches where we scored some good goals in the second period. In the third, we were on our heels a little bit. They came at us pretty good there in the third, and we weathered that one. [Bobrovsky] had a big save. It was a good win all the way around."