Forty-one seconds later, after a turnover at the Edmonton line, Eberle and McDavid broke away on a 2-on-1. Using McDavid as a decoy, Eberle avoided a diving Ottawa wing Bobby Ryan and put his shot over Anderson's right shoulder.
Eberle scored on the power play at 11:16 when McDavid threaded a pass from the goal line to Anderson's left between Ottawa defenseman Cody Ceci and Mark Borowiecki and onto Eberle's stick in the slot.
The Oilers power play was 3-for-3; The Senators entered the game with the 30th-ranked penalty kill in the NHL.
"Our power play has kind of been the catalyst for our team. We've scored five goals in the last two games," Eberle said. "That's key. Any time you have a good power play, it causes the other team, I don't want to say play soft, but they want to be a little bit aware of how they are going to play and not take penalties. That's been huge."
Hoffman and Stone scored to make it 3-2 in the second period, but the Oilers then scored the next four goals.