Arizona's lone win this season came vs. the Flyers on Oct. 15 in the team's season/home opener.
Louis Domingue will start in goal for the Coyotes, who rank 30th in the NHL in goals against per game at 4.33. Domingue is 0-4-0 with a 5.03 goals-against average and a .851 save percentage.
"Louis is a little like our team," Tippett said. "He's had stretches where he made some good saves, but at the end of the day, the two winning goals - (vs.) the Islanders and New York (Rangers) - were both stoppable goals."
He added: "We need more saves to stabilize our group, and we need sustained ability to stay with the game for longer periods of time. If we do that, we'll be fine."
Oliver Ekman-Larsson will enter the game leading NHL defensemen in goals with four.
Thursday's game is a homecoming of sorts for Coyotes defenseman Luke Schenn, whose brother Brayden plays for Philadelphia. Luke played 213 games for the Flyers from 2012-16.
"We played Philly the first game of the year, and he was suspended so we didn't get the chance to play against each other," Schenn said. "We have played against each other before. It was before obviously I'd been traded to the Flyers and I was in Toronto. We've done it before but obviously played with each other for a while. That was a lot of fun, and now we're on opposite teams and it's going to be another fun game and really looking forward to it."
Forward Ryan White played 107 games for the Flyers from 2014-16.
Philadelphia (3-3-1) is looking to build off a dramatic, come-from-behind win over Buffalo on Tuesday, in which the Flyers trailed by three goals after two periods. They rallied to win 4-3 in a shootout.
Captain Claude Giroux will enter the game with a six-game point streak and leading the NHL with eight assists.
Steve Mason is expected to start in goal. Mason owns a 5-9-1 record vs. the Coyotes; he was the losing goalie on Oct. 15 when he allowed four goals on 35 shots.
Forward Dale Weise is eligible to return to the Flyers lineup after serving a three-game NHL suspension.
The Flyers, who are celebrating their 50th year in the League this season, will honor members of the team's Hall of Fame before the game.
READ OFFICIAL GAME NOTES
BROADCAST INFO:
TV: FOX Sports Arizona
Radio: ESPN Phoenix 620 AM
COYOTES PROJECTED LINEUP VS. FLYERS:
Forwards
Domi - Hanzal - Vrbata
McGinn - Martinook - Duclair
Rieder - Richardson - Doan
Dauphin - Dvorak - White
Defensemen
Ekman-Larsson - Murphy
Goligoski - Stone
Chychrun - Schenn
Goalies
Domingue
Peters
