Binnington missed seven games in COVID-19 protocol but served as the backup to Charlie Lindgren in Fridays' 4-1 win against the Dallas Stars.
"He feels good, he's had some practices, he feels like he's ready to go," Blues Head Coach Craig Berube said. "I trust him."
In his last meeting against the Jets, Binnington turned in one of the season's best performances, making 39 saves and stopping all four shooters in the shootout to help the Blues to a 3-2 win against Winnipeg in their only previous meeting of the season.
Berube said the Blues would use 11 forwards and seven defensemen for the game with Oskar Sundqvist out (COVID-19). That means means Scott Perunovich will return.
Below is a projected lineup for Sunday.