Avalanche coach Jared Bednar said the atmosphere surrounding the pregame ceremony to retire Milan Hejduk's No. 23 contributed to the decisive win.
"It was a great look at some of the history of this proud franchise," Bednar said. "Our guys really enjoyed it, and we talked to them about our preparation coming out of that. You see all the fans packed in the building and they're already cheering before the game starts. It gets your emotions up, and our guys came out and they played a passionate, spirited, good affair."
Eric Staal scored two goals for the Wild (22-17-3), who are 4-2-0 in their past six games but have lost four in a row on the road.
"We took a step back today," Minnesota coach Bruce Boudreau said. "We got to learn how to win on the road. That's ridiculous how we can play so good at home and completely opposite on the road."
Colorado took a 1-0 lead on Bourque's first goal of the season at 7:38 of the first period, and Nemeth made it 2-0 at 18:16.
The Wild closed to 2-1 when Staal scored on the rebound of Jonas Brodin's shot with 32.8 seconds left in the first, but the Avalanche were in control the rest of the way.