The Flames came into the night second in league goal differential, sporting an impressive +31 mark. The Panthers were fifth at +27.
Calgary had the best road record at 13-4-2, with the eighth-best points percentage (.667).
Florida was the No.-1 home team in the NHL at 17-3-0, sitting second in the NHL (.719).
There were plenty of offensive chances to go around in a back-and-forth affair (49 shots for Calgary, 45 for Florida), the Cats scoring a pair of powerplay goals and converting on more of their chances en route to a 6-2 victory in Sunrise, Fla, on Tuesday night.
Johnny Gaudreau continued his torrid scoring streak for the Flames, while Blake Coleman also tallied and had a career-high 12 shots. Jacob Markstrom was busy and put in a great performance making 39 saves.
Sergei Bobrovsky was dialled in at the other end of the ice, stopping 47 of the pucks he faced.
The Panthers got an early powerplay at 4:42 when Noah Hanifin was whistled for a hook on Gustav Forsling, who had tried to split the Calgary defence on a breakout.
Just past the midway point of the advantage, Chris Tanev tried to clear a puck from in front of the net but Patric Hornqvist smacked it in.
Matthew Tkachuk sprung Gaudreau with a beautiful stretch pass and No. 13 hit the jets to pull away from two defenders and snap his 14th of the season glove-high past Bobrovsky 1:05 later to tie it up.
Gaudreau came into the tilt riding a 10-game point streak on the road after back-to-back three-point performances in the team's last two victories over Seattle and Chicago. He's now notched a point in all but three road games this season.