Mats Zuccarello did knot the game at 13:27, but a penalty on the very next shift put Nashville back on the power play, where it promptly capitalized on Ryan Johansen's first of the night just 35 seconds after the Wild had drawn even.
Another power-play goal by Johansen with under a minute to play in the first gave the Preds a 3-1 lead after 20 minutes.
At 5-on-5, Minnesota was the superior team all night. Unfortunately, it couldn't keep the game even-up for long enough stretches to make a difference. The Wild set a club record with 49 shots on goal in the game, besting the previous mark of 48.
"It's such a contrast. We talked about it after the Washington game and even the Carolina game, if games stay like that, we're real good," said Wild coach Dean Evason. "If it turns into a special teams, skill matchup, and we feel we have skill. We're built for 5 on5 and although we have to get better if and when we get to the playoffs, that's the type of game it's going to be. So we like our group."
Nashville made it 4-1 on a goal by Philip Tomasino six minutes into the second, just a few seconds after a Nashville power play had expired.
"It wasn't good," Wild forward Marcus Foligno said of the team's penalty kill. "Ekker and I we've got to be better. Give credit to them, they've got a lot of great players on that unit ... But it's tough. You look at all those penalties and some of them are wishy washy. Give us one or two back and it's a different game, right?"