Nashville, which lost playoff series to Chicago in 2015 and 2010, and lost four of five regular-season games this season, was all too familiar with this scenario.
The Predators had the lead but needed to be perfect on the penalty kill, considering the Blackhawks have two power-play units that are the envy of most teams.
The Blackhawks took the ice with a swagger in their stride as the United Center faithful bellowed for an equalizer.
The game rested with Nashville's penalty killers. If they wanted to win the game, if they wanted to record the first road shutout in their history, they had to deliver.
Defense had defined the Predators to this point. They blocked shots, took away time and space and kept the Blackhawks, for the most part, to the perimeter. Now they had to do it again if they wanted to take a series lead into Game 2 in Chicago on Saturday.
"Obviously you want to kill a penalty every time but up by one late in the third period, it's a huge kill," defenseman Ryan Ellis said.
Ellis began the effort by blocking a Brent Seabrook shot. The puck exited the zone and the Blackhawks had to regroup, but Watson broke up another attack.
"Generally, as a penalty killer, you want to take away time and space, especially with the skilled guys they have over there," Watson said. "If you give them a ton of time they are going to be able to make plays."
Chicago gained the zone again but Ellis cleared the puck, and the forechecking of Calle Jarnkrok killed additional time.
On Chicago's next rush, Nashville's Mattias Ekholm dove to push away a dangerous centering pass, Jarnkrok cleared a loose puck away from the net, P.K. Subban won yet another 50-50 race to the puck and Roman Josi blocked a shot from Anisimov.
The power play ended without the Blackhawks getting a shot on goal.