After Moritz Seider stole the puck from a retreating Easton Cowan in the neutral zone, the Red Wings defenseman fed Larkin in the slot, where he shot past Joseph Woll’s blocker.
Simon Edvinsson scored, and Larkin added an assist for the Red Wings (31-16-4), who are 7-1-0 in their past eight games. John Gibson made 30 saves for his seventh straight win, improving to 16-2-0 in his past 18 starts.
Scott Laughton scored, and Woll made 39 saves for the Maple Leafs (24-17-9), who are 1-2-2 in their past five games.
Detroit forward Patrick Kane did not have a point and remains two away from tying Mike Modano (1,374) for the most points by a United States-born player in NHL history.
The Maple Leafs went up 1-0 at 4:46 of the first period. Calle Jarnkrok fanned on a one-timer at the right face-off dot off a pass from Steven Lorentz but inadvertently directed the puck to Laughton, who shot from the top of the crease past Gibson’s blocker.
Edvinsson tied it 1-1 at 19:42 when he took a pass from Lucas Raymond, who was at the bottom of the right face-off circle, and shot past Woll’s blocker in the slot.
Laughton had a chance to give the Maple Leafs the lead at 16:41 of the second period on a penalty shot but lost control of the puck and did not get off a strong shot.
Toronto defenseman Oliver Ekman-Larsson left the game at 8:57 of the first period with a lower-body injury after his right leg appeared to get twisted when he got tangled up with Raymond.
