Balinskis tied it 3-3 with a power-play goal at 18:59. Reinhart sent a pass to Balinskis in the right circle from below the goal line, and Balinskis beat Lyon to the short side with a quick snap shot.
Zucker put the Sabres back in front 4-3 at 5:31 of the third period, finishing Doan's feed from below the goal line with a wrist shot from low in the left circle on the power play.
The Panthers got a 5-on-3 power play for a little more than a minute with 6:52 remaining, but Lyon and the Sabres stood their ground.
“We did a great job limiting their chances to the outside,” Lyon said. “Just grinded through it. It was an emotional part of the game, we just hardened ourselves and got the job done. That’s all you can do.’’
Doan then extended the lead to 5-3 at 17:51. Krebs rushed down the left side and sent a centering pass to Doan, who tapped it over Bobrovsky's glove from in tight.
“Just stick with it," Krebs said. “We have had great resiliency in our game and we know we are a good hockey team that can score goals."
Florida, which was already down a number of top forwards, including Brad Marchand and Anton Lundell, played most of the game without center Sam Bennett, who left the game after the first period with an upper-body injury.
Maurice did not have an immediate update on Bennett, saying “we’ll get a better handle on it tomorrow.”
“It seems like someone is getting injured every night," said Tkachuk, who missed 47 games while recovering from surgery to repair a torn adductor muscle and sports hernia before returning on Jan. 19.
NOTES: Lyon won his eighth straight road game dating to Dec. 9, which is the longest run by a goalie in Sabres history. ... Vilmanis and Balinskis both scored, marking the first time in NHL history two Latvia-born players on the same team scored in a single game. The two will represent Latvia in the upcoming Olympic Winter Games Milano Cortina 2026.