The Bruins allowed the first two goals of the game before scoring four times. It was the first multigoal comeback win for Boston in a Cup Final game since the Bruins entered the NHL in 1924.
Here's a look at the comebacks, overtimes and other unpredictable events in Game 1 of the Cup Final from 2010-18.
RELATED: [Complete Stanley Cup Final coverage]
2018: The Vegas Golden Knights and Washington Capitals traded the lead four times, a first in Stanley Cup Final history. Vegas won 6-4, earning a victory in its first Cup Final game.
2017:The Nashville Predators came back from three goals down to tie the Pittsburgh Penguins 3-3 before Jake Guentzel scored the go-ahead goal with 3:17 remaining in the third period. The Penguins won 5-3.
2016:The San Jose Sharks rallied from two goals down to tie the Penguins 2-2, but Nick Bonino scored with 2:33 left in the third period to give Pittsburgh a 3-2 victory.
2015: The Chicago Blackhawks trailed the Tampa Bay Lightning 1-0 with less than seven minutes remaining in the third period before Teuvo Teravainen and Antoine Vermette scored 1:58 apart to give the Blackhawks a 2-1 road win.
2014:The Los Angeles Kings trailed the New York Rangers 2-0 late in the first period. But goals by Kyle Clifford and Drew Doughty forced overtime, and Justin Williams completed the comeback at 4:36 of overtime with his first NHL playoff OT goal for a 3-2 win.
2013: The Blackhawks trailed the Bruins 3-1 early in the third period. Goals by Dave Bolland and Johnny Oduya tied the score, and the Blackhawks won 4-3 when Andrew Shaw scored at 12:08 of the third overtime. It's the fifth-longest game in Cup Final history.
2012: The Kings improved to 9-0 on the road during the 2012 playoffs when Anze Kopitar scored 8:13 into overtime for a 2-1 victory against the New Jersey Devils.
2011: Raffi Torres scored at 19:41 of the third period, the latest winning goal in regulation of a Stanley Cup Final game since 1992, to give the Vancouver Canucks a 1-0 victory against the visiting Bruins.
2010:The Blackhawks and Philadelphia Flyers combined for 11 goals in the highest-scoring Cup Final game since 1992. There were five goals scored in the first and second periods each before Chicago's Tomas Kopecky got the only goal in the third for a 6-5 victory.