Vegas reached the second round Tuesday when it completed a sweep against the Los Angeles Kings with a 1-0 win.
It was the second Stanley Cup Playoff sweep in Sharks history. San Jose swept the Vancouver Canucks five years ago in the first round.
They outscored the Ducks 16-4 in the series, and goaltender Martin Jones made 128 saves on 132 shots (.970 save percentage). The four goals-against set a Sharks record for fewest allowed by a goalie in a playoff series.
"When you put a team up against a wall like that, you know they're going to come with a push," Jones said of Game 4. "They gave us everything they had, and it was tough. But the guys did a great job. We had a couple of huge penalty kills, huge blocked shots, and it was a gutsy way to win there."
The Sharks were 1-2-1 against the Golden Knights in the regular season.
"They're a fast team," Jones said. "They come at you with all four lines. They forecheck hard, and they're just a tenacious, hardworking team. So we need to make sure that we're prepared properly here and ready to go right from the start of Game 1."
Tomas Hertl, who scored the game-winning goal Wednesday at 9:09 of the third period, praised Jones.
"[Jones] was amazing all series," Hertl said. "Again, he was the best player for us. … [The Golden Knights had] a great season. I was watching when they played every other night (in the playoffs). They play really good, really fast. [Goalie Marc-Andre] Fleury is like [Jones], he was great all series. He was amazing too.
"But we have to be ready, be all over him on the ice. They play fast and they really like to play in their building. For sure, tough series. But we can handle it."