The 31-year-old center has missed the past three games with an upper-body injury sustained in a 4-2 loss to the New Jersey Devils on Nov. 13.
"I feel good. I'm glad," Crosby said Wednesday after the morning skate. "I'm excited to get back in the lineup and get out there."
Crosby is tied for second on the Penguins with eight goals and is third with 19 points in 16 games.
He said the Penguins (7-8-4), who are 1-7-2 in their last 10 games, are working hard to turn things around.
"It's never easy when you're losing games," Crosby said. "I think guys get frustrated and I think it's just a matter of getting through that."
The Penguins went 0-2-1 without Crosby, including a 5-4 overtime loss to the Buffalo Sabres on Monday in which they led 4-1 in the second period.
Crosby will skate on the first line with left wing Jake Guentzel and right wing Patric Hornqvist and said it shouldn't take him long to get his timing back.
"It's not going to happen in the first five shifts, but if I have that same mentality and go out there, and play the right way, I think stuff will come fairly quick," he said. "That's what I expect."
Crosby said Penguins need to simplify their game in order to start winning again.
"It's just little mistakes. Sometimes you make mistakes and they're little ones," he said. "Guys can find a way to bail each other out. I think in this case, talking about maybe the last week or so, we've given up some pretty big chances and ones that are hard to recover from.
"They haven't been always the same thing. If they were, I think we would have solved it. So I think it's just a matter of finding that consistency everywhere in our game."
