Radulov gave Dallas a 3-2 lead at 10:32 on a one-timer off a pass from Jamie Benn following a turnover by Panthers defenseman Mike Matheson, and he made it 4-2 at 19:20 when he was awarded a goal after Mike Hoffman threw his stick to prevent him from scoring into an empty net.
Ben Bishop, who missed the previous two games because of a lower-body injury, made 20 saves, Benn had a goal and two assists, and Tyler Seguin had four assists for the Stars (38-29-6), who are 7-2-1 in their past 10 games. Dallas leads the Arizona Coyotes by four points for the first wild card into the Stanley Cup Playoffs from the Western Conference and trails the St. Louis Blues by two points for third place in the Central.
WATCH: [All Panthers vs. Stars highlights]
Aleksander Barkov scored two goals, and Sam Montembeault made 33 saves for the Panthers (32-29-12), who have lost two in a row and are eight points behind the Columbus Blue Jackets for the second wild card into the playoffs from the Eastern Conference.
"You never want to give up, you never know," Panthers forward Jonathan Huberdeau said about the playoffs. "But we've got to play for pride, for us, for each other. We've got to play until the end. That's what we want to do."
Barkov gave Florida a 1-0 lead at 2:11 of the first period with a redirection of Huberdeau's shot along the right wall. The goal ended Bishop's shutout streak at 233:03, the longest in Stars/Minnesota North Stars history.