Vegas is in third place in the Pacific Division, 12 points behind first-place Calgary and nine behind the second-place San Jose Sharks. The Golden Knights are eight points ahead of the Arizona Coyotes.
Goalie Marc-Andre Fleury, who has back-to-back shutouts, will start for Vegas. He has not allowed a goal in 168:43 and is one win from tying Jacques Plante (437) for eighth place on the NHL's all-time wins list.
David Rittich is expected to start in goal for the Flames, who've lost back-to-back games in regulation after a seven-game winning streak. Calgary is three points ahead of San Jose for first place in the division and the Western Conference.