Trailing the Sabres 4-1 midway through the second period, the Lightning rallied with five unanswered goals to defeat the Sabres on Tuesday in Buffalo.
Alex Killorn and Tyler Johnson paced the Lightning offense, leading Tampa Bay to a 6-4 victory and fourth-straight win.
It was Buffalo that got off to the fast start, however, capping a first period of heavy pressure with a goal in the final minute. Conor Sheary wired a one-timed shot past Andrei Vasilevskiy after Curtis Lazar stepped up and intercepted a pass at the blueline.
The teams went back-and-forth in a wild second period.
Marcus Johansson doubled Buffalo's lead early on, scoring with a shot from the wing.
Video: TBL@BUF: Palat sends the puck home with quick rip
Ondrej Palat got Tampa Bay on the board at the end of a power play seven minutes into the period. It was Tyler Johnson who made the play, feeding Palat who was open in the slot.
After Jimmy Vesey and Jack Eichel scored for the Sabres to stretch their lead to three, Tampa Bay answered back with a pair of goals to pull back within one.
Killorn finished from in close on a power play and Johnson beat Linus Ullmark on a breakaway late in the period to make it 4-3 through 40 minutes.
Tampa Bay's momentum carried over into the third period, as the Bolts scored twice in two minutes to take their first lead of the game.
Kevin Shatttenkirk tied the game at four, getting a lucky bounce with his shot deflecting off a Buffalo defender and past Ullmark. 1:48 later, Pat Maroon fed Killorn from below the goalline for a goal to put the Bolts up 5-4.
Anthony Cirelli poured in an empty net goal with three seconds remaining in regulation to round out the scoring.
Video: TBL@BUF: Johnson beats the defense for breakaway goal
Killorn led the way with two goals and assist. Johnson also had three points, with his goal ending a five-game goalless drought.
The win gives Tampa Bay a sweep of the regular season series versus the Sabres and marks their 12th-straight win over Atlantic Division teams this season.
The Bolts resume the road trip on Thursday night against the Canadiens in Montreal.
TBL | 19:03 Conor Sheary (6) - Curtis Lazar
BUF | 2:12 Marcus Johansson (6) - Conor Sheary, Marco Scandella
TBL | 7:00 Ondrej Palat (12) - Tyler Johnson, Mikhail Sergachev - PPG
BUF | 8:12 Jimmy Vesey (5) - Marcus Johansson, Conor Sheary
BUF | 9:56 Jack Eichel (25) - Unassisted - SHG
TBL | 13:57 Alex Killorn (14) - Brayden Point, Nikita Kucherov - PPG
TBL | 16:55 Tyler Johnson (8) - Carter Verhaeghe, Ryan McDonagh
TBL | 6:20 Kevin Shattenkirk (6) - Tyler Johnson, Anthony Cirelli
TBL | 8:08 Alex Killorn (15) - Pat Maroon, Cedric Paquette
TBL | 19:57 Anthony Cirelli (9) - Alex Killorn, Steven Stamkos - EN