Evgeni Malkin and Tommy Novak each had two assists for the Penguins (22-14-10), who had scored two total goals in three straight losses (0-2-1). Stuart Skinner made 30 saves.
Matvei Michkov, Rodrigo Abols and Nick Seeler scored, and Denver Barkey had two assists for the Flyers (22-16-8), who have been outscored 25-9 during a five-game losing streak (0-4-1), and have allowed at least five goals in the past four. They lost 5-2 at the Buffalo Sabres on Wednesday.
Sam Ersson allowed three goals on 14 shots before being replaced in the second period by Aleksei Kolosov, who made 13 saves in relief.
Justin Brazeau put Pittsburgh ahead 1-0 with seven seconds left on a power play at 2:16 of the first period, tapping in a pass from Ben Kindel.
Bryan Rust made it 2-0 at 12:25 with a wrist shot from the top of the left face-off circle past Ersson’s glove on another power play.
Egor Chinakhov extended the lead to 3-0 at 1:16 of the second period, taking a pass from Malkin for a wrist shot in the slot.
Abols answered back 1:01 later, cutting the deficit to 3-1 at 2:17 by deflecting a slap shot from Cam York.
Kolosov replaced Ersson following the goal.
Blake Lizotte made it 4-1 at 18:29. Noel Acciari drove to the net for a backhand, producing a rebound that he tipped over Kolosov on a second attempt that Lizotte batted out of the air.
Crosby took a cross-ice pass from Malkin for a wrist shot from one knee at the bottom of the right circle for his 25th goal, pushing the lead to 5-1 on a power play at 3:10 of the third period.
Connor Dewar scored on a shot through Kolosov’s five-hole to make it 6-1 at 4:27.
Seeler pulled the Flyers to within 6-2 at 10:54, and Michkov finished a feed from Barkey at 17:25 for the 6-3 final.
