Namestnikov, who was also acquired on Feb. 24 in a trade from the Ottawa Senators, tied it 1-1 at 12:50 when he kicked a rebound into shooting position from the edge of the crease.
The Red Wings had back-to-back power plays early in the second period, including 15 seconds of 5-on-3, but couldn't take the lead.
"We generated a few chances, but probably not enough," Blashill said. "We had a good stretch when we put Larkin's group back out there for the 5-on-3 and the start of the second 5-on-4, but then we shot ourselves in the foot by missing a seam pass."
Gabriel Landeskog set up Colorado's second goal at 14:31, taking an open-ice hit in order to send a saucer pass to O'Connor for a breakaway.
"That's just a selfless play and it shows you why he's wearing the C," O'Connor said of Landeskog. "He saw we had a good look and he was willing to take the hit to get me the puck."