The center last played in a 3-2 win against the Chicago Blackhawks on Nov. 9 before having core muscle surgery Nov. 14. He has 17 points (five goals, 12 assists) in 17 games this season.
The Penguins, who are six points behind the first-place Washington Capitals in the Metropolitan Division, are 18-6-4 without Crosby this season. They have won three in a row, seven of their past nine (7-1-1) and 14 of their past 18 (14-3-1).
The Wild are 0-2-1 in their past three games, and 1-4-1 in their past six after winning three of their previous four (3-1-0). They have scored one goal in each of their past two games, a 2-1 loss to the Calgary Flames on Thursday and a 4-1 loss to the Vancouver Canucks on Sunday.
Goalie Devan Dubnyk will start a second straight game for Minnesota after making 26 saves Sunday.