At 16:42 of the second period in the Maple Leafs/Red Wings game, Toronto requested a Coach's Challenge to review whether Gustav Nyquist interfered with goaltender Frederik Andersen before Detroit's goal.
After reviewing all available replays and consulting with NHL Hockey Operations staff, the Referee confirmed no goaltender interference infractions occurred.

Therefore the original call stands - good goal Detroit Red Wings.
Since the Coach's Challenge did not result in the original call being overturned, the Toronto Maple Leafs forfeit their time-out.