Matt Duchene scored two power-play goals, but the Predators were the recipients of some favorable bounces and netted the game-winner early in the third period on a 5-on-3 power play.
"For me, that was the hardest we played--that was the best game we played in a couple weeks," said Avalanche head coach Jared Bednar. "We had some chances to square that game up, and it was a tough way to fall behind on the 5-on-3."
Colorado came back three times to tie the contest but faced a tricky situation late in the second period when it had to kill a full two-minute, 5-on-3 penalty. The Avs held on for the final 43 seconds of the stanza and denied the Predators' chances for the first 1:04 of the new period, but they couldn't kill the entire two-man disadvantage as Roman Josi scored with 13 seconds left on the infraction.
The Avalanche battled hard in the third to try and knot the game one more time. The club had 13 shots in the frame and had a power-play chance with 1:33 left, which then became a 6-on-4 advantage when goaltender Semyon Varlamov went to the bench for the extra attacker.
Despite Colorado's best efforts, Nashville held on.
"We were desperate. We wanted to tie that game. We wanted to send that game to OT and get a point," Duchene said. "It's really disappointing we weren't able to find that goal to do it. The last 10 seconds, I thought we had it on our stick and it didn't happen. It's disappointing, but at the same time we got to try and keep our heads up and be positive."