Tomas Hertl, Jack Eichel, William Karlsson and Trevor Connelly scored for the Golden Knights (6-2-0), who ended a four-game winning streak with a 4-2 loss at the Minnesota Wild on Monday. Rasmus Andersson has two assists, and Adin Hill made 25 saves.
Ryan O’Reilly had a goal and an assist, and Adam Edstrom scored for Nashville (2-2-2). Juuse Saros made 20 saves.
O’Reilly put the Predators up 1-0 at 3:55 of the first period. Filip Forsberg put the puck on net from the left face-off circle, and the rebound went right to O'Reilly in front, where he backhanded it into an open net.
Hertel answered to tie it 1-1 at 6:46 with a wrist shot over Saros’ blocker from the left circle just after a Nashville power play had ended.
Eichel tipped in a cross-ice pass from Brayden McNabb as he drove the net at 12:48 to put the Golden Knights ahead 2-1.
Jack Drury had a chance to tie it at 13:09, but Hill stopped his wrist shot attempt on a penalty shot.
Edstrom scored the first short-handed goal of his career at 8:45 of the second period to make it 2-2.
After losing the puck on a breakaway, he regained possession off the end boards and maneuvered himself in front and slipped a shot past Hill far side. Nicolas Hague assisted on the goal for his first point in his sixth game with Nashville.
Karlsson, after collecting his first goal of the season on Monday, roofed a wrist shot from the right circle into the left corner to help Vegas regain a 3-2 lead at 17:44.
Connelly finished a cross-ice pass from Noah Hanifin to make it 4-2 at 4:49 of the third period, and Howden deflected a shot between his legs that went in off the left post for the 5-2 final at 6:24.
