Edmonton Oilers at Ottawa Senators, 5 p.m. ET (NBCSN, TVAS, TSN5, SNW)
It's the first of back-to-back games with the Oilers leading the season series 7-0-0. Edmonton forward Leon Draisaitl has scored 17 points (seven goals, 10 assists) against Ottawa this season.
Montreal Canadiens at Toronto Maple Leafs, 7:30 p.m. ET (NBCSN, SN, RDS, NHL.TV)
Maple Leafs goalie Jack Campbell can tie Carey Price of the Montreal Canadiens (10 games in 2016-17) for the longest season-opening winning streak by a goalie in NHL history. Campbell is 9-0-0 with a 1.53 goals-against average and .944 save percentage this season.
Vegas Golden Knights at St. Louis Blues, 9 p.m. ET (ESPN+, BSMW, ATTSN-RM, NHL.TV)
The Blues have lost three straight and are 0-6-1 in their past seven games after a 6-1 loss to the Golden Knights on Monday. Vegas goalie Marc-Andre Fleury is one win from tying Ed Belfour (484) for fourth in NHL history.
Colorado Avalanche at Minnesota Wild, 9 p.m. ET (ESPN+, BSN, BSWI+, ALT, NHL.TV)
Avalanche center Nathan MacKinnon has scored 10 points (four goals, six assists) in a six-game point streak and leads Colorado with 12 points (two goals, 10 assists) in six games against the Wild, who will have forwards Zach Parise and Mats Zuccarello back in the lineup.
Arizona Coyotes at Los Angeles Kings, 10 p.m. ET (BSW, BSAZ+, NHL.TV)
The Coyotes can become the first NHL team since the Washington Capitals in 2009-10 to have a hat trick in three consecutive games. Arizona defenseman Jakob Chychrun (Sunday against the Anaheim Ducks) and forward Michael Bunting (Monday against the Kings) each scored a hat trick in the previous two games.