| PLAYER | INJURY | DATE OF INJURY | GAMES MISSED | RETURN |
| Carson Soucy | Upper-body | 2/21/20 | 9 | -- |
| Luke Kunin | Upper-body | 2/21/20 | 5 | 3/3 |
| Carson Soucy | Illness | 2/6/20 | 2 | 2/9 |
| Mikko Koivu | Illness | 1/18/20 | 2 | 1/22 |
| Brad Hunt | Illness | 1/14/20 | 4 | Healthy 1/22 |
| Jason Zucker | Fractured right fibula | 12/15/19 | 10 | 1/12 |
| Greg Pateryn | Lower-body | 12/4/19 | 14 | Activated from IR 1/9 |
| Mikko Koivu | Lower-body | 12/3/19 | 12 | 12/31 |
| Joel Eriksson Ek | Upper-body | 12/14/19 | 4 | 12/23 |
| Jared Spurgeon | Upper-body | 12/3/19 | 7 | 12/19 |
| Marcus Foligno | Lower-body | 11/7/19 | 10 | 12/1 |
| Luke Kunin | Illness | 11/9/19 | 1 | 11/12 |
| Devan Dubnyk | Upper-body | 10/22/19 | 2 | 10/29 |
| Jordan Greenway | Upper-body | 10/24/19 | 2 | 10/29 |
| Kevin Fiala | Lower-body | 10/20/19 | 3 | 10/29 |
| Joel Eriksson Ek | Lower-body | 10/17/19 | 3 | 10/26 |
| Victor Rask | Lower-body | 10/15/19 | 3 | 10/24 |
| Mats Zuccarello | Lower-body | 10/12/19 | 4 | 10/22 |
| Greg Pateryn | Core muscle | 10/1/19 | 27 | Assigned to Iowa on conditioning assignment 12/2 |
| Total Games Lost | 124 |