Domi was selected by the Coyotes with the No. 12 pick in the 2013 NHL Draft, and it didn't take him long to make his mark in the League. In 2015-16, his first NHL season, Domi finished second on the Coyotes with 52 points and tied with Oliver Ekman-Larsson for the most assists (34).
The son of longtime NHL tough guy Tie Domi, he had his first NHL goal and assist in his League debut, a 4-1 win against the Los Angeles Kings on Oct. 9, 2015. On Jan. 12, 2016, Domi had his first NHL hat trick, in a 4-3 win against the Edmonton Oilers. He had five multigoal games and 12 multipoint games.