The first-place Canucks hope to beat the second-place Avalanche for the second time in six days as the teams meet up at GM Place.
The Canucks, who are one win away from their first three-game winning streak since a five-game run from Oct. 28-Nov. 5, hold a six-point lead over Calgary and Colorado in the division.
Colorado, which has won nine straight division titles, hasn't made up much ground in the standings of late, going 4-3-5 in December.
Vancouver, which topped Colorado 3-2 last Monday, is coming off a 4-3 overtime win over Chicago on Wednesday.
"We got to understand that we have to put teams away early. We can't let teams stick around," Bertuzzi said. "To let them back in the game was a mistake on our part, but we're fortunate to get two points out of it."
Vancouver has lost just two of its last 12 games (7-2-3).
The Avalanche, meanwhile, are coming off a 2-1 win over Calgary on Wednesday.
"We can't rely on Joe (Sakic) and Peter (Forsberg)'s line all the time because every night, every team is going out there to stop them," Worrell said. "We've got some good players on other lines and we have to be able to chip in."
Aebischer improved to 15-7-5.
"He's playing good for us right now," Colorado defenseman Adam Foote said of his goaltender. "He's focused and giving us a chance to win. We're fortunate to have him back there for us playing the way he is."
Colorado won for just the second time in nine games (2-3-4).