The visiting Red Wings dominated rookie goaltender Malcolm Subban, Pavel Datsyuk had a goal and three assists, and Henrik Zetterberg scored twice to spoil the Bruins' first preseason game at TD Garden.
"No matter what I did, the pucks just found its way in," Subban told the Boston Globe. "Some bad bounces, but I didn't do my part tonight."
Zetterberg scored once in each of the first two periods, then had an assist as Datsyuk capped Detroit's four-goal third period. Jimmy Howard played the first two periods and stopped 14 of 15 shots.
Jarome Iginla and Nick Johnson had goals for Boston. Subban, the Bruins' first-round pick (No. 24) in the 2012 NHL Draft, went all the way and stopped 20 shots.
"We wanted him to fight through it," coach Claude Julien said. "This is a good learning thing for a goaltender, to see that this is what he's going to be facing. He's got to fight through those situations."