Hockey Fights Cancer Night, hosted in partnership with the Courage of Carly Fund at Roswell Park Cancer Institute, is part of the NHL's annual initiative to raise money and awareness toward cancer research.
It also serves as an outlet for players to honor their loved ones who have battled the disease.
READ: A message from Karin Housley
"Cancer affects everyone. I'm no exception," Sabres defenseman Marco Scandella said. "I lost my dad a couple of years ago, so it's a special night for me. Everybody knows somebody who's been affected. It's a big night and I'm just going to play hard tonight."
Scandella's father, Francesco, passed away following a bout with prostate cancer in 2015.
"I just think about him every day," Scandella said. "He taught me everything I know. He was just a great example for me on how to be a man, so I just take that with me and I play with that every game and try to make him proud."
The lavender jerseys that the Sabres will wear during warmups will be available at auctions.nhl.com immediately following the game, and autographed Hockey Fights Cancer hats will be available for $20 at KeyBank Center. All fans in attendance on Saturday will receive a commemorative lavender scarf.
If you can't make it to the game, coverage on MSG-B begins at 6:30 p.m. with the GMC Gamenight Pregame Show. You can also listen live on WGR 550, with puck drop set for shortly after on 7 p.m.