Joining the Bills in 2016, Alexander, already a seasoned NFL veteran, quickly established himself as a leader in the locker room and champion in the community. The linebacker earned several accolades during his four-season stint with the Bills, including an All-Pro Second-Team selection in 2016, a season in which he amassed 12.5 sacks, and a 2017 Pro Bowl nod, where he was named the 2017 Pro Bowl Defensive MVP. Well-respected by his teammates, Alexander was also voted as a captain in 2017, 2018 and 2019 and was named the Bills Walter Payton Man of the Year nominee three consecutive times.