DETROIT -- It's beginning to look like the beginning of the season again for the Red Wings with veteran defensemen going down.
Defenseman Danny DeKeyser suffered an upper-body injury late in the second period and the team announced at the start of the third that he would not return to the game.
During a Tampa Bay power play, DeKeyser blocked Steven Stamkos' shot and appeared to be in pain as the period ended.
After the game, Wings coach Jeff Blashill had grim news.
"I'll have a better update tomorrow," Blashill said. "He'll be out for, I'm just going to call it multiple weeks."
It is the second such injury for DeKeyser, who missed eight games from Oct. 15-Nov. 1 with an upper-body injury.
"That's a big loss for us," defenseman Niklas Kronwall said. "He logs a lot of minutes, plays a lot of defensive situations, plays against the other teams' top lines every night. It's a big loss for us for sure."
DeKeyser was second on the team in average time on ice at 21:34, just behind Mike Green's 21:52.
The Wings were already missing veteran Trevor Daley, who left the game Nov. 28 against St. Louis in the first period with a lower-body injury.
Daley has missed the last three games and has not yet returned to practice.
The Wings were already playing with 11 forwards and seven defensemen as Anthony Mantha is out 4-6 weeks after undergoing hand surgery Tuesday afternoon and Tyler Bertuzzi is out for two games due to a league suspension.
The team called up forward Wade Megan before the game.
Forward Darren Helm is also out with a shoulder injury.