DETROIT - The Red Wings had been relatively healthy for a while but that could be at an end.
Darren Helm took a hit from Colorado defenseman Erik Johnson at 5:08 of the second period and was very slow to get up.
Although he left the ice under his own power, Helm was favoring his left leg and immediately went down the tunnel to the dressing room.
During a commercial break later in the second, Helm returned to the ice to test the injury but went back to the dressing room immediately after.
The Wings announced before the third period that Helm had a lower-body injury and would not return to the game.
"Lower-body injury, day to day," Wings coach Jeff Blashill said after the game. "I don't know more than that. I can't necessarily say whether to expect him on Monday. I just don't know."
Helm already missed 28 games earlier this season due to a dislocated shoulder.
Tomas Nosek had been called up on an emergency basis because of a couple of players that were uncertain before warmups but only Mitch Callahan did not take the ice.
Nosek was assigned to the AHL's Grand Rapids Griffins but could be back soon if Helm's injury is more serious.