Daley immediately went down and athletic trainer Piet Van Zant rushed out to attend to him.
Although Daley was able to get up and skate off with some help, the Wings announced before the second period that he would not return due to an upper-body injury.
"We'll see tomorrow," Wings coach Jeff Blashill said after the game. "It's hard for me to say whether it was a stinger or whether it's anything more serious. He's going to get an MRI tomorrow at 10, so I'll know way more after that. I'm hoping it was just a stinger, but we'll see."
Although the Wings still had Danny DeKeyser, Niklas Kronwall, Jonathan Ericsson, Nick Jensen, Mike Green and Xavier Ouellet, Daley was missed.
"Just the great puck-moving defenseman, a guy that's great at making the first pass out of the zone and a guy that can get up and skate and play," goaltender Jimmy Howard said.
Luke Witkowski is still serving his 10-game suspension so he is not available.
"If you have 11 forwards and get a forward hurt, that hurts you a little bit but certainly having the seven D gave up six for the game and I thought we had a number of D play well," Blashill said, "I thought Jensen was great tonight, so real good for him."