Coach Alain Vigneault said Girardi, who has two goals and 15 assists in 74 games, is day-to-day with an upper-body injury. His status for the regular-season finale Saturday against the Detroit Red Wings is unclear.
"We'll see how he feels and go from there," Vigneault said Thursday after the morning skate.
The Rangers are already without defenseman Ryan McDonagh, who is out for at least the next two games after injuring his hand blocking a shot in a 4-2 win Monday against the Columbus Blue Jackets.
Defenseman Dan Boyle, who was rested against the Lightning, is back in the lineup against the Islanders.
The Rangers lead the Islanders by two points for third place in the Metropolitan Division. The Islanders, currently the first wild card into the Stanley Cup Playoffs from the Eastern Conference, have a game in hand.
