Mrazek went on to finish with 21 saves on 23 shots.
At 9:35, Brett Pesce sent a one-timer from beyond the left circle past Sergei Bobrovsky to cut Carolina's deficit down to 2-1. Then, at 14:20, Martin Necas took a pass from Dougie Hamilton and buried a one-timer of his own to even things up at 2-2 heading into the first intermission.
In the second period, Hamilton scored at 17:45 to put the Hurricanes on top 3-2.
"We got a good start, but we didn't take care of it," Panthers coach Joel Quenneville said.
Entering the night ranking second in the league in third-period goals (32), Florida unfortunately couldn't find the goal it needed to tie the game over the final 20 minutes of regulation. Keeping the team within striking distance, however, Bobrovsky made 16 of his 30 total saves in the third.
With 1:02 left in regulation, Andrei Svechnikov cashed in on an empty-netter for the 4-2 final.
"It was a tight game," Bobrovsky said. "Unfortunately, we didn't get the points tonight."
Just their sixth regulation loss through 23 games, the Panthers, who saw their three-game winning streak snapped with tonight's defeat, still sit at a very solid 12-6-5 on the season.
Here are five takeaways from Saturday's loss in Raleigh…