Tippett confirmed that a few Oilers have been cleared to play, which would result in some changes to the lineup.
"We've got a couple of people that are ready to go. So, there's a good chance we'll see some changes there," he said.
The bench boss also confirmed Mike Smith would start in goal.
The Oilers held an optional skate in the morning. Lines will be made apparent at warmups.
-- Paul Gazzola, EdmontonOilers.com
OILERS (8-4-1) vs BLUE JACKETS (5-4-2)
TV: 5:30 p.m. MT; Televised on Sportsnet One & 360
The Oilers and Blue Jackets will meet twice this season. After Wednesday's contest, the two clubs will have to wait until March 7 to conclude their season series at Rogers Place.
In both meetings last season, the Oilers were up to the task. Edmonton outscored Columbus 8-1 in respective 4-1 and 4-0 wins, with Leon Draisaitl doing the majority of the damage with a goal and five assists. Zack Kassian had two goals across both contests, and Mikko Koskinen helped secure both victories from between the pipes with 49 saves on 50 shots.
Oilers team scope:
A strong third period that saw the Oilers out-shoot the Detroit Red Wings 17-5 wasn't enough to complete the comeback on Tuesday in what concluded as a 3-1 road loss for the Orange & Blue.
The club quickly packed their bags and headed for Columbus, set to compete in the second of a back-to-back. This will mark the first back-to-back of seven on the season.
Despite Edmonton's loss to Detroit, the club remains atop the Pacific Division with an 8-4-1 record and 17 points, with Connor McDavid and Leon Draisaitl pacing the scoring with 22 points apiece.
Blue Jackets team scope:
The Blue Jackets receive the Oilers for the second game of their back-to-back, keen to start a new point streak after having a six-game run (5-0-1) snapped at the hands of the Philadelphia Flyers in a 7-4 loss on Saturday.
An important part of that run was the play of 21-year-old Pierre-Luc Dubois, who has five goals for the Jackets in his last eight games.
But Columbus' loss in the city of Brotherly Love included two more names in Ryan Murray and Alexandre Texier added to a growing injury list that includes alternate captain Brandon Dubinsky and Finnish blueliner Markus Nutivaara.
By the Numbers:
The Oilers are 5-0-0 when scoring first. ... Edmonton's road power play is fifth in the League with a 30 percent rate, going 6-for-20. ... The club is 22nd in faceoff percentage with a 48.1 percentage. ... The Oilers are fifth in blocked shots with 195. ... The team is sixth in giveaways with 164 but fourth in takeaways with 104.
Columbus is 27th in goals for with 30 and 10th in goals against, allowing 39. ... The Blue Jackets have an 11.4 percent power-play percentage at the moment, going 4-for-35 this season. ... Columbus has let in three shorthanded goals against this year, which is tied for first in the NHL.
OILERS - Joel Persson (concussion) is day-to-day; Adam Larsson (fibula) is on IR; Josh Archibald (foot fracture) is on IR; Joakim Nygard (ribs) is on IR.
BLUE JACKETS - Brandon Dubinsky (wrist) is on IR; Markus Nutivaara (lower body) is day-to-day; Alexandre Texier (knee) is on IR; Sonny Milano (mouth) is day-to-day; Ryan Murray (fractured hand) is on IR.