The Oilers return home for a match against the San Jose Sharks on Thursday. The game can be seen on Sportsnet West and heard on the Oilers Radio Network, including 630 CHED. Puck drop is 7:08 p.m. MDT.
"It's not the loss, it's the chase that wears you down," said Oilers Head Coach Ken Hitchcock post-game.
Coming in on the heels of a back-to-back, the Oilers scored twice in the opening period, with Lucic and Nurse getting the Orange & Blue on the board.
Lucic vacated the front of the Avs' net, screening goaltender Semyon Varlamov. Matt Benning whipped a point shot at the goal and Lucic was able to get the tip at the top of the crease to score his sixth marker of the year at 9:20, while the Avs were still looking for their first shot on goal.
Then, The Doc went to work. Nurse displayed his edges while maneuvering through the Avs' zone, finding himself to the left of Varlamov on the goal-line. The defender released a wrister that banked in off Varlamov's blocker, notching his ninth tally of the year and 40th point.
Nurse's point marked the first time since 2008-09 that an Oilers defender reached the 40-point mark, with Tom Gilbert and Sheldon Souray both achieving the feat that year.
Nugent-Hopkins registered assists on both goals, as the Oilers took their 2-0 lead into the middle frame.
"We played a great first period," said Hitchcock.
The Avs overwrote their two-goal deficit with a four-goal flurry in the second, getting three consecutive power plays to come out with a 4-2 lead to enter the third.
"You can't kill three penalties in a row like that and we paid for it," said Hitchcock, whose club finished the night 2-for-3 on the penalty kill.
Nathan MacKinnon got the Avs on the board first, getting through three Oilers while on the man advantage and going glove side for his 40th of the year.
Exactly one minute after, Tyson Barrie launched a shot from the right side that eluded Koskinen, knotting the game at 2-2.
Alexander Kerfoot then gave the Avs the lead, tapping home a puck that went from Erik Johnson to Matt Nieto then Kerfoot on the doorstep.