The Penguins, 6-2-2 in their past 10 games, are in second place in the division, five points behind the Washington Capitals, one ahead of the third-place Columbus Blue Jackets and two ahead of the fourth-place Flyers, who trail the Capitals by seven points.
Philadelphia, 3-0-1 in its past four games after going 1-6-1 in its previous eight, is two points ahead of the New Jersey Devils for the first wild card into the Stanley Cup Playoffs from the Eastern Conference.
The Flyers have allowed five goals in each of their three losses to the Penguins this season; Pittsburgh won 5-4 in overtime at PPG Paints Arena on Nov. 27, and 5-1 on Jan. 2 and 5-2 on March 7 at Wells Fargo Center.